"目录号: HY-14859
Dipraglurant (ADX 48621)是mGluR5拮抗剂，IC50为21 nM。
相关产品
CTEP-LY341495-LY354740-LY404039-RG7090-Mavoglurant-MPEP Hydrochloride-Topiramate-JNJ-40411813-L-Glutamine-FITM-JNJ16259685-MTEP hydrochloride-(S)-MCPG-ADX-47273-
生物活性
Description
Dipraglurant (ADX 48621) is a mGluR5 antagonists with IC50 of 0.021 μM. IC50 Value: 0.021 μM [1]Target: mGluRDipraglurant (ADX-48621) from Addex Therapeutics showed in vivo activity in different anxiety models in rat50 and is currently in phase II for the treatment of dyskinesia in Parkinson's disease.
Clinical Trial
Addex Pharma S.A.
Parkinson's Disease
April 2011
Phase 2
Johns Hopkins University-Addex Pharma S.A.
Healthy
April 2015
Phase 1
Addex Pharma S.A.
Parkinson's Disease
April 2011
Phase 2
Johns Hopkins University-Addex Pharma S.A.
Healthy
April 2015
Phase 1
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References
