电信的网速使用apt-get都会ping不上，索性更改国内源
打开apt的文件夹
```shell
cd /etc/apt
```
编辑源
vim ./sources.list
点击i进入编辑模式，逐条更新，包括网址后面的命令。
# See http://help.ubuntu.com/community/UpgradeNotes for how to upgrade to
# newer versions of the distribution.
deb http://mirrors.aliyun.com/ubuntu/ trusty main restricted universe multiverse
# deb-src http://archive.ubuntu.com/ubuntu/ bionic main restricted ## Major bug fix updates produced after the final release of the
## distribution.
deb http://mirrors.aliyun.com/ubuntu/ trusty-security main restricted universe multiverse
# deb-src http://archive.ubuntu.com/ubuntu/ bionic-updates main restricted ## N.B. software from this repository is ENTIRELY UNSUPPORTED by the Ubuntu
## team. Also, please note that software in universe WILL NOT receive any
## review or updates from the Ubuntu security team.
deb http://mirrors.aliyun.com/ubuntu/ trusty-updates main restricted universe multiverse
# deb-src http://archive.ubuntu.com/ubuntu/ bionic universe
deb http://mirrors.aliyun.com/ubuntu/ trusty-proposed main restricted universe multiverse
# deb-src http://archive.ubuntu.com/ubuntu/ bionic-updates universe ## N.B. software from this repository is ENTIRELY UNSUPPORTED by the Ubuntu
## team, and may not be under a free licence. Please satisfy yourself as to
## your rights to use the software. Also, please note that software in
## multiverse WILL NOT receive any review or updates from the Ubuntu
## security team.
deb http://mirrors.aliyun.com/ubuntu/ trusty-backports main restricted universe multiverse
# deb-src http://archive.ubuntu.com/ubuntu/ bionic multiverse
deb-src http://mirrors.aliyun.com/ubuntu/ trusty main restricted universe multiverse
# deb-src http://archive.ubuntu.com/ubuntu/ bionic-updates multiverse ## N.B. software from this repository may not have been tested as
## extensively as that contained in the main release, although it includes
## newer versions of some applications which may provide useful features.
## Also, please note that software in backports WILL NOT receive any review
## or updates from the Ubuntu security team.
deb-src http://mirrors.aliyun.com/ubuntu/ trusty-security main restricted universe multiverse
# deb-src http://archive.ubuntu.com/ubuntu/ bionic-backports main restricted universe multiverse ## Uncomment the following two lines to add software from Canonical's
## 'partner' repository.
## This software is not part of Ubuntu, but is offered by Canonical and the
## respective vendors as a service to Ubuntu users.
# deb http://archive.canonical.com/ubuntu bionic partner
# deb-src http://archive.canonical.com/ubuntu bionic partner deb-src http://mirrors.aliyun.com/ubuntu/ trusty-updates main restricted universe multiverse
# deb-src http://security.ubuntu.com/ubuntu/ bionic-security main restricted
deb-src http://mirrors.aliyun.com/ubuntu/ trusty-proposed main restricted universe multiverse
# deb-src http://security.ubuntu.com/ubuntu/ bionic-security universe
deb-src http://mirrors.aliyun.com/ubuntu/ trusty-backports main restricted universe multiverse
# deb-src http://security.ubuntu.com/ubuntu/ bionic-security multiverse
安装conda，更新conda源为清华镜像
43 bash Anaconda3-2019.10-Linux-x86_64.sh -b -f -p ~/conda
44 echo 'export PATH="/anaconda3/bin:$PATH"'>>/.bashrc
45 sudo echo 'export PATH="/anaconda3/bin:$PATH"'>>/.bashrc
46 echo 'export PATH="~/anaconda3/bin:$PATH"'>>~/.bashrc
47 source ~/.bashrc
48 conda deactivate
49 conda config --add channels conda-forge # Lowest priorit
50 conda config --add channels r # Optional
51 conda config --add channels defaults
52 conda config --add channels bioconda
53 conda config --add channels
54 conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/bioconda/
55 conda config --set show_channel_urls yes
56 conda create -y -n transcriptome r-base=3.4.3 python=2.7
57 conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/msys2/
58 conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/cloud/conda-forge/
59 conda config --add channels https://mirrors.tuna.tsinghua.edu.cn/anaconda/pkgs/free/
60 conda config --set show_channel_urls yes
