2020-02-26 R语言的蛋白质组学包

现在Bioconductor version 3.11中有 132个 蛋白质组学 和 88个 质谱包 。其它的非Bioconductor包在 r Biocexptpkg("RforProteomics")中有介绍,用R打开RforProteomics() 或者在线阅读。

R包太多了自己慢慢看、慢慢试用!!!

132个蛋白质组学包,大部分都没有用过😝,保存备查。

Package Title Version
artMS artMS Analytical R tools for Mass Spectrometry 1.5.0
ASEB ASEB Predict Acetylated Lysine Sites 1.31.0
AssessORF AssessORF Assess Gene Predictions Using Proteomics and Evolutionary Conservation 1.5.0
bioassayR bioassayR Cross-target analysis of small molecule bioactivity 1.25.0
biobroom biobroom Turn Bioconductor objects into tidy data frames 1.19.0
BioNetStat BioNetStat Biological Network Analysis 1.7.0
biosigner biosigner Signature discovery from omics data 1.15.0
BRAIN BRAIN Baffling Recursive Algorithm for Isotope distributioN calculations 1.33.0
calm calm Covariate Assisted Large-scale Multiple testing 1.1.0
Cardinal Cardinal A mass spectrometry imaging toolbox for statistical analysis 2.5.0
CausalR CausalR Causal network analysis methods 1.19.0
CellNOptR CellNOptR Training of boolean logic models of signalling networks using prior knowledge networks and perturbation data 1.33.0
ChemmineOB ChemmineOB R interface to a subset of OpenBabel functionalities 1.25.0
ChemmineR ChemmineR Cheminformatics Toolkit for R 3.39.0
cisPath cisPath Visualization and management of the protein-protein interaction networks. 1.27.0
cleaver cleaver Cleavage of Polypeptide Sequences 1.25.0
clippda clippda A package for the clinical proteomic profiling data analysis 1.37.0
CNORdt CNORdt Add-on to CellNOptR: Discretized time treatments 1.29.0
CNORfeeder CNORfeeder Integration of CellNOptR to add missing links 1.27.0
CNORode CNORode ODE add-on to CellNOptR 1.29.0
customProDB customProDB Generate customized protein database from NGS data, with a focus on RNA-Seq data, for proteomics search 1.27.0
cydar cydar Using Mass Cytometry for Differential Abundance Analyses 1.11.0
DAPAR DAPAR Tools for the Differential Analysis of Proteins Abundance with R 1.19.0
deco deco Decomposing Heterogeneous Cohorts using Omic Data Profiling 1.3.0
deltaGseg deltaGseg deltaGseg 1.27.0
DEP DEP Differential Enrichment analysis of Proteomics data 1.9.0
DEqMS DEqMS a tool to perform statistical analysis of differential protein expression for quantitative proteomics data. 1.5.0
diffcyt diffcyt Differential discovery in high-dimensional cytometry via high-resolution clustering 1.7.0
DominoEffect DominoEffect Identification and Annotation of Protein Hotspot Residues 1.7.0
Doscheda Doscheda A DownStream Chemo-Proteomics Analysis Pipeline 1.9.0
drawProteins drawProteins Package to Draw Protein Schematics from Uniprot API output 1.7.0
EGSEA EGSEA Ensemble of Gene Set Enrichment Analyses 1.15.0
eiR eiR Accelerated similarity searching of small molecules 1.27.0
fCI fCI f-divergence Cutoff Index for Differential Expression Analysis in Transcriptomics and Proteomics 1.17.0
fmcsR fmcsR Mismatch Tolerant Maximum Common Substructure Searching 1.29.0
GraphPAC GraphPAC Identification of Mutational Clusters in Proteins via a Graph Theoretical Approach. 1.29.0
HPAanalyze HPAanalyze Retrieve and analyze data from the Human Protein Atlas 1.5.0
hpar hpar Human Protein Atlas in R 1.29.0
IMMAN IMMAN Interlog protein network reconstruction by Mapping and Mining ANalysis 1.7.0
InterMineR InterMineR R Interface with InterMine-Powered Databases 1.9.0
iPAC iPAC Identification of Protein Amino acid Clustering 1.31.0
IPPD IPPD Isotopic peak pattern deconvolution for Protein Mass Spectrometry by template matching 1.35.0
isobar isobar Analysis and quantitation of isobarically tagged MSMS proteomics data 1.33.0
kimod kimod A k-tables approach to integrate multiple Omics-Data 1.15.0
KinSwingR KinSwingR KinSwingR: network-based kinase activity prediction 1.5.0
KnowSeq KnowSeq A R package to extract knowledge by using RNA-seq raw files 1.1.0
limma limma Linear Models for Microarray Data 3.43.0
LPEadj LPEadj A correction of the local pooled error (LPE) method to replace the asymptotic variance adjustment with an unbiased adjustment based on sample size. 1.47.0
MassSpecWavelet MassSpecWavelet Mass spectrum processing by wavelet-based algorithms 1.53.0
mixOmics mixOmics Omics Data Integration Project 6.11.0
MSGFgui MSGFgui A shiny GUI for MSGFplus 1.21.0
MSGFplus MSGFplus An interface between R and MS-GF+ 1.21.0
msmsEDA msmsEDA Exploratory Data Analysis of LC-MS/MS data by spectral counts 1.25.0
msmsTests msmsTests LC-MS/MS Differential Expression Tests 1.25.0
MSnbase MSnbase Base Functions and Classes for Mass Spectrometry and Proteomics 2.13.0
MSnID MSnID Utilities for Exploration and Assessment of Confidence of LC-MSn Proteomics Identifications 1.21.0
MSstats MSstats Protein Significance Analysis in DDA, SRM and DIA for Label-free or Label-based Proteomics Experiments 3.19.0
MSstatsQC MSstatsQC Longitudinal system suitability monitoring and quality control for proteomic experiments 2.5.0
MSstatsQCgui MSstatsQCgui A graphical user interface for MSstatsQC package 1.7.0
MSstatsSampleSize MSstatsSampleSize Simulation tool for optimal design of high-dimensional MS-based proteomics experiment 1.1.0
MSstatsTMT MSstatsTMT Protein Significance Analysis in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling 1.5.0
mzID mzID An mzIdentML parser for R 1.25.0
mzR mzR parser for netCDF, mzXML, mzData and mzML and mzIdentML files (mass spectrometry data) 2.21.0
NormalyzerDE NormalyzerDE Evaluation of normalization methods and calculation of differential expression analysis statistics 1.5.0
omicRexposome omicRexposome Exposome and omic data associatin and integration analysis 1.9.0
OmicsLonDA OmicsLonDA Omics Longitudinal Differential Analysis 1.1.0
oppti oppti Outlier Protein and Phosphosite Target Identifier 1.1.0
PAA PAA PAA (Protein Array Analyzer) 1.21.0
Path2PPI Path2PPI Prediction of pathway-related protein-protein interaction networks 1.17.0
pathview pathview a tool set for pathway based data integration and visualization 1.27.0
pathwayPCA pathwayPCA Integrative Pathway Analysis with Modern PCA Methodology and Gene Selection 1.3.0
PCpheno PCpheno Phenotypes and cellular organizational units 1.49.0
PECA PECA Probe-level Expression Change Averaging 1.23.0
pepXMLTab pepXMLTab Parsing pepXML files and filter based on peptide FDR. 1.21.0
PGA PGA An package for identification of novel peptides by customized database derived from RNA-Seq 1.17.0
pgca pgca PGCA: An Algorithm to Link Protein Groups Created from MS/MS Data 1.11.0
phosphonormalizer phosphonormalizer Compensates for the bias introduced by median normalization in phosphoproteomics 1.11.0
plgem plgem Detect differential expression in microarray and proteomics datasets with the Power Law Global Error Model (PLGEM) 1.59.0
PLPE PLPE Local Pooled Error Test for Differential Expression with Paired High-throughput Data 1.47.0
PowerExplorer PowerExplorer Power Estimation Tool for RNA-Seq and proteomics data 1.7.0
ppiStats ppiStats Protein-Protein Interaction Statistical Package 1.53.0
PrInCE PrInCE Predicting Interactomes from Co-Elution 1.3.0
proBAMr proBAMr Generating SAM file for PSMs in shotgun proteomics data 1.21.0
proBatch proBatch Tools for Diagnostics and Corrections of Batch Effects in Proteomics 1.3.0
PROcess PROcess Ciphergen SELDI-TOF Processing 1.63.0
procoil procoil Prediction of Oligomerization of Coiled Coil Proteins 2.15.0
proFIA proFIA Preprocessing of FIA-HRMS data 1.13.0
pRoloc pRoloc A unifying bioinformatics framework for spatial proteomics 1.27.0
pRolocGUI pRolocGUI Interactive visualisation of spatial proteomics data 1.21.0
ProteomicsAnnotationHubData ProteomicsAnnotationHubData Transform public proteomics data resources into Bioconductor Data Structures 1.17.0
ProteoMM ProteoMM Multi-Dataset Model-based Differential Expression Proteomics Analysis Platform 1.5.0
ProtGenerics ProtGenerics S4 generic functions for Bioconductor proteomics infrastructure 1.19.0
pulsedSilac pulsedSilac Analysis of pulsed-SILAC quantitative proteomics data 1.1.0
Pviz Pviz Peptide Annotation and Data Visualization using Gviz 1.21.0
qcmetrics qcmetrics A Framework for Quality Control 1.25.0
qPLEXanalyzer qPLEXanalyzer Tools for qPLEX-RIME data analysis 1.5.0
QuartPAC QuartPAC Identification of mutational clusters in protein quaternary structures. 1.19.0
rain rain Rhythmicity Analysis Incorporating Non-parametric Methods 1.21.0
RankProd RankProd Rank Product method for identifying differentially expressed genes with application in meta-analysis 3.13.0
RCASPAR RCASPAR A package for survival time prediction based on a piecewise baseline hazard Cox regression model. 1.33.0
Rcpi Rcpi Molecular Informatics Toolkit for Compound-Protein Interaction in Drug Discovery 1.23.0
ReactomeGSA ReactomeGSA Client for the Reactome Analysis Service for comparative multi-omics gene set analysis 1.1.0
ropls ropls PCA, PLS(-DA) and OPLS(-DA) for multivariate analysis and feature selection of omics data 1.19.0
RpsiXML RpsiXML R interface to PSI-MI 2.5 files 2.29.0
rpx rpx R Interface to the ProteomeXchange Repository 1.23.0
rScudo rScudo Signature-based Clustering for Diagnostic Purposes 1.3.0
rTANDEM rTANDEM Interfaces the tandem protein identification algorithm in R 1.27.0
sapFinder sapFinder A package for variant peptides detection and visualization in shotgun proteomics. 1.25.0
SBGNview SBGNview Overlay omics data onto SBGN pathway diagram 1.1.0
ScISI ScISI In Silico Interactome 1.59.0
SDAMS SDAMS Differential Abundant Analysis for Metabolomics and Proteomics Data 1.7.0
shinyTANDEM shinyTANDEM Provides a GUI for rTANDEM 1.25.0
SLGI SLGI Synthetic Lethal Genetic Interaction 1.47.0
SMAD SMAD Statistical Modelling of AP-MS Data (SMAD) 1.3.0
SpacePAC SpacePAC Identification of Mutational Clusters in 3D Protein Space via Simulation. 1.25.0
sparsenetgls sparsenetgls Using Gaussian graphical structue learning estimation in generalized least squared regression for multivariate normal regression 1.5.0
statTarget statTarget Statistical Analysis of Molecular Profiles 1.17.0
SubCellBarCode SubCellBarCode SubCellBarCode: Integrated workflow for robust mapping and visualizing whole human spatial proteome 1.3.0
SWATH2stats SWATH2stats Transform and Filter SWATH Data for Statistical Packages 1.17.0
synapter synapter Label-free data analysis pipeline for optimal identification and quantitation 2.11.0
tofsims tofsims Import, process and analysis of Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) imaging data 1.15.0
TPP TPP Analyze thermal proteome profiling (TPP) experiments 3.15.0
TPP2D TPP2D FDR-controlled analysis of 2D-TPP experiments 1.3.0
XINA XINA Multiplexes isobaric mass tagged-based kinetics data for network analysis 1.5.0
proteoQC proteoQC An R package for proteomics data quality control 1.23.0
specL specL specL - Prepare Peptide Spectrum Matches for Use in Targeted Proteomics 1.21.0
ROTS ROTS Reproducibility-Optimized Test Statistic 1.15.0
readat readat Functionality to Read and Manipulate SomaLogic ADAT files 1.13.0
topdownr topdownr Investigation of Fragmentation Conditions in Top-Down Proteomics 1.9.0
phemd phemd Phenotypic EMD for comparison of single-cell samples 1.3.0
proDA proDA Differential Abundance Analysis of Label-Free Mass Spectrometry Data 1.1.0
MBQN MBQN Mean/Median-balanced quantile normalization 1.1.0
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