http://mooc.guokr.com/note/17258/
11.1 错配修复Introduction to DNA MIsmatch Repair错配修复（MMR）
从此开始讲DNA修复。dna错配有两种类型：复制错误和DNA损伤
11.2 错配识别
错配识别由一种称为MutS的蛋白质介导
11.3MutS Recognition
MutS把错配的位点识别出来
11.4 Methyl-Directed Nascent Strand Detection
通过甲基化修饰来识别新生链，大肠杆菌中。因为新生链是未被甲基化的链。
甲基化位点为了保护大肠杆菌的DNA使其不在GATC位点被切
11.5MutH Recognition
MutH酶执行辨认工作。是一个在GATC位点切割未甲基化链的内切酶。从而会切割错配的新生链。
11.6 缺口介导的新生链检测Nick-Directed Nascent Strand Detection
利用了新DNA有缺口的特点。检测滑行夹是否存在
11.7MutL Regulation in Other Organisms
11.8 Choosing Which Strand to Repair
11.9Methyl-Directed Strand Repair
11.10Nick-Directed Strand Repair
11.10bAdditional Information
12.1Methyl-Directed MMR Assays
12.2Interpreting Methyl-Directed MMR Assay Results
12.3 In Vivo Reversion Assays
12.4In Vitro MMR Assay
12.5In Vitro MMR Incision Assay and Methylation Detection
