使用方法参考大佬写的就行 https://www.jianshu.com/p/dfe35a2a02d4
作者总结了一些pathway的LR pair,我们可以直接拿来使用。
LR_database
加载进去是这样的
几个pathway的LR数量如下
可以使用这些分类信息进行文章crosstalk bubble plot的展示,比如这篇文章
The ligand-receptor pairs in CellChat retrieved from previous studies were divided into four groups including, cytokine/chemokine, immune checkpoint, growth factor, and others [37]. The crosstalk between cell analyses conducted via “CellChat” was as follows: (1) “createCellChat” function was applied to create “CellChat” object; (2) the “computeCommunProb,” “computeCommunProbPathway,” and “aggregateNet” functions were adopted to infer the cellular communication network; (3) “netVisual_aggregate,” “netVisual_signalingRole,” and “netVisual_bubble” were adopted to visualize crosstalk among cells.
文章地址:https://doi.org/10.1016/j.ebiom.2021.103459