B 受到疼痛傷害 產生inflamattion(紅腫熱痛)後
同一地方對於疼痛的閾值會下降(因為inflammator cytokine,eg interleukin1 sensitize nociceptor到) 使產生inflammation pain
A Mechanical force=nociceptive=activate high threshold high nociceptive pain
C Neuropathic pain (.burning .針扎.paresthesia. Dysthesia. Spontaneous)
-任何peripheral nerve damage導致疼痛 (inhibition signal degenerate),spontaneous的 pain
Dm polyneuropathy, neuritis,切到
D central sensitization (排除peripheral)
Fibromyalgia. Traumatic pain
以自述方式評估
Dysfuntional
Central dysinhibition
長期centrall sensitization